Insights into Kinesin-1 Activation from the Crystal Structure of KLC2 Bound to JIP3.

Cockburn JJB, Hesketh SJ, Mulhair P, Thomsen M, O'Connell MJ, Way M.

Structure 26:1486-1498.e6. 2018 

doi: 10.1016/j.str.2018.07.011.  PMID:30197037

Septins suppress the release of vaccinia virus from infected cells.

Pfanzelter J, Mostowy S, Way M.

Journal of Cell Biology 217:2911-2929. 2018

doi:10.1083/jcb.201708091  PMID: 29921601

Tuning of in vivo cognate B-T cell interactions by Intersectin 2 is required for effective anti-viral B cell immunity.

Burbage M, Gasparrini F, Aggarwal S, Gaya M, Arnold J, Nair U, Way M, Bruckbauer A, Batista FD.

Elife 2018 7. pii: e26556.

doi:10.7554/eLife.26556. PMID: 29337666

Myofibril contraction and crosslinking drive nuclear movement to the periphery of skeletal muscle.

Roman W, Martins JP, Carvalho FA, Voituriez R, Abella JVG, Santos NC, Cadot B, Way M, Gomes ER.

Nature Cell Biology 19:1189-1201. 2017

doi: 10.1038/ncb3605. PMID:28892082

RhoD Inhibits RhoC-ROCK-Dependent Cell Contraction via PAK6.

Durkin CH, Leite F, Cordeiro JV, Handa Y, Arakawa Y, Valderrama F, Way M.

Developmental Cell 41:315-329 2017

doi: 10.1016/j.devcel.2017.04.010. PMID:28486133

Cytoplasmic ATR Activation Promotes Vaccinia Virus Genome Replication.

Postigo A, Ramsden AE, Howell M, Way M.

Cell Reports 19:1022-1032. 2017

doi:10.1016/j.celrep.2017.04.025. PMID: 28467896

APC/C Dysfunction Limits Excessive Cancer Chromosomal Instability.

Sansregret L, Patterson JO, Dewhurst S, López-García C, Koch A, McGranahan N, Chao WCH, Barry DJ, Rowan A, Instrell R, Horswell S, Way M, Howell M, Singleton MR, Medema RH, Nurse P, Petronczki M, Swanton C.

Cancer Discovery 7:218-233. 2017

doi: 10.1158/2159-8290.CD-16-0645. PMID:28069571

NPF motifs in the vaccinia virus protein A36 recruit intersectin-1 to promote Cdc42:N-WASP-mediated viral release from infected cells.

Snetkov X, Weisswange I, Pfanzelter J, Humphries AC, Way M.

Nature Microbiology 1:16141. 2016

doi:10.1038/nmicrobiol.2016.141. PMID: 27670116

Mitochondria mediate septin cage assembly to promote autophagy of Shigella.

Sirianni A, Krokowski S, Lobato-Márquez D, Buranyi S, Pfanzelter J, Galea D, Willis A, Culley S, Henriques R, Larrouy-Maumus G, Hollinshead M, Sancho-Shimizu V, Way M, Mostowy S.

EMBO Reports 17:1029-43. 2016

doi:10.15252/embr.201541832. PMID: 27259462

Suppression of NYVAC Infection in HeLa Cells Requires RNase L but Is Independent of Protein Kinase R Activity.

Fernández-Escobar M, Nájera JL, Baldanta S, Rodriguez D, Way M, Esteban M, Guerra S.

Journal of Virology 90:2135-41. 2015

doi: 10.1128/JVI.02576-15. PMID: 26656695

Isoform diversity in the Arp2/3 complex determines actin filament dynamics.

Abella JV, Galloni C, Pernier J, Barry DJ, Kjær S, Carlier MF, Way M.

Nature Cell Biology 18:76-86. 2016

doi:10.1038/ncb3286. PMID: 26655834

Wiskott-Aldrich Syndrome Interacting Protein Deficiency Uncovers the Role of the Co-receptor CD19 as a Generic Hub for PI3 Kinase Signaling in B Cells.

Keppler SJ, Gasparrini F, Burbage M, Aggarwal S, Frederico B, Geha RS, Way M, Bruckbauer A, Batista FD.

Immunity 43:660-73. 2015

doi: 10.1016/j.immuni.2015.09.004. PMID:26453379

Structure of the Complex of F-Actin and DNGR-1, a C-Type Lectin Receptor Involved in Dendritic Cell Cross-Presentation of Dead Cell-Associated Antigens.

Hanč P, Fujii T, Iborra S, Yamada Y, Huotari J, Schulz O, Ahrens S, Kjær S, Way M, Sancho D, Namba K, Reis e Sousa C.

Immunity 42:839-849. 2015

doi: 10.1016/j.immuni.2015.04.009. PMID:25979418

Open source software for quantification of cell migration, protrusions, and fluorescence intensities

Barry DJ, Durkin CH, Abella JV, Way M.

Journal of Cell Biology 209:163-80. 2015 doi:10.1083/jcb.201501081. PMID:25847537

The Escherichia coli effector EspJ blocks Src kinase activity via amidation and ADP ribosylation.

Young JC, Clements A, Lang AE, Garnett JA, Munera D, Arbeloa A, Pearson J, Hartland EL, Matthews SJ, Mousnier A, Barry DJ, Way M, Schlosser A, Aktories K, Frankel G.

Nature Communications  5:5887. 2014

doi:10.1038/ncomms6887. PMID:25523213

KSHV-TK is a tyrosine kinase that disrupts focal adhesions and induces Rho-mediated cell contraction

Gill MB, Turner R, Stevenson PG, Way M.

EMBO Journal 34:448-65. 2015

doi:10.15252/embj.201490358. PMID:25471072

Ena/VASP proteins cooperate with the WAVE complex to regulate the actin cytoskeleton.

Chen XJ, Squarr AJ, Stephan R, Chen B, Higgins TE, Barry DJ, Martin MC, Rosen MK, Bogdan S, Way M.

Developmental Cell  30:569-84. 2014

doi:10.1016/j.devcel.2014.08.001. PMID:25203209

Cdc42 and the Rho GEF intersectin-1 collaborate with Nck to promote N-WASP-dependent actin polymerisation.

Humphries AC, Donnelly SK, Way M.

Journal Cell Science 127:673-85. 2014

doi: 10.1242/jcs.141366. PMID:24284073


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